About the CCKP
The Cancer Complexity Knowledge Portal (CCKP) is an open access repository generated by multiple collaborative programs focused on advancing cancer research.
The CCKP was created through a multi-consortium effort between Sage Bionetworks, the Cancer Systems Biology Consortium (CSBC) and the Physical Sciences in Oncology Network (PS-ON), with sponsorship by the National Cancer Institute (NCI) of the National Institutes of Health (NIH). Today, Sage Bionetworks leads the NCI-funded Multi-Consortia Coordinating (MC2) Center and has expanded the CCKP to reflect coordination efforts across several NCI Division of Cancer Biology (DCB)-funded programs including the Cancer Systems Biology Consortium (CSBC), the Physical Sciences in Oncology Network (PS-ON), the Cancer Tissue Engineering Collaborative (TEC), Cellular Cancer Biology Imaging Research (CCBIR), the Metastasis Research Network (MetNet), and the Patient-Derived Models of Cancer (PDMC) program.
Together, these efforts are working to understand tumor biology, treatment options, and patient outcomes.
What makes the CCKP valuable
The CCKP integrates resources from several specialized NCI DCB-funded consortia programs to create a powerful platform that’s addressing cancer's most complex challenges.
Multidisciplinary Integration
The CCKP unites computational modeling, physical sciences, tissue engineering, advanced imaging, metastasis research, and patient-derived models under one platform. The CCKP provides access to difficult-to-find internal and external sources in the domain of cancer research and experimentation.
Comprehensive Data Ecosystem
The CCKP provides a holistic view of cancer that spans from molecular mechanisms to tissue-level dynamics by connecting systems biology insights with physical and engineering perspectives.
Translational Bridge
The CCKP helps disseminate and connect fundamental research to clinical applications to help researchers translate discoveries about tumor complexity, heterogeneity, and microenvironment into potential therapeutic strategies.
Collaborative Framework
The CCKP breaks down traditional research silos to foster cross-disciplinary collaboration that accelerates discovery in cancer research.
How Sage Bionetworks, Synapse, and the CCKP work together
Sage Bionetworks
Sage Bionetworks a non-profit organization based in Seattle, Washington that serves as the MC2 Center for NCI DCB-funded consortia programs. As the MC2 Center, Sage supports engagement and resource sharing within the cancer research community by maintaining the CCKP.
Synapse
Sage Bionetworks developed the Synapse data sharing platform as part of our work in advocating open science. Synapse unlocks collaborative data curation, analysis, and computational modeling. It allows users to upload, store, analyze, and privately track data before releasing to the public-facing CCKP. Think of Synapse as the CCKP’s backend data warehouse.
CCKP
The CCKP is the access point to find or discover research data, publications, grants, and other relevant resources. The CCKP makes complex data accessible to the scientific community, as well as the public, in a straightforward user interface (UI).